Peptide-Based Treatment: A Promising Cancer Therapy

Autor: Yu-Feng Xiao, Meng-Meng Jie, Bo-Sheng Li, Chang-Jiang Hu, Rui Xie, Bo Tang, Shi-Ming Yang
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Immunology Research, Vol 2015 (2015)
Druh dokumentu: article
ISSN: 2314-8861
2314-7156
DOI: 10.1155/2015/761820
Popis: Many new therapies are currently being used to treat cancer. Among these new methods, chemotherapy based on peptides has been of great interest due to the unique advantages of peptides, such as a low molecular weight, the ability to specifically target tumor cells, and low toxicity in normal tissues. In treating cancer, peptide-based chemotherapy can be mainly divided into three types, peptide-alone therapy, peptide vaccines, and peptide-conjugated nanomaterials. Peptide-alone therapy may specifically enhance the immune system’s response to kill tumor cells. Peptide-based vaccines have been used in advanced cancers to improve patients’ overall survival. Additionally, the combination of peptides with nanomaterials expands the therapeutic ability of peptides to treat cancer by enhancing drug delivery and sensitivity. In this review, we mainly focus on the new advances in the application of peptides in treating cancer in recent years, including diagnosis, treatment, and prognosis.
Databáze: Directory of Open Access Journals
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