Low vitamin D status is associated with nonalcoholic Fatty liver disease independent of visceral obesity in Korean adults.

Autor: Ji A Seo, Chai Ryoung Eun, Hyunjoo Cho, Seung Ku Lee, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Hyung Joon Yim, Chol Shin, Nan Hee Kim
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: PLoS ONE, Vol 8, Iss 10, p e75197 (2013)
Druh dokumentu: article
ISSN: 1932-6203
64533565
DOI: 10.1371/journal.pone.0075197
Popis: To investigate the association between serum 25-hydroxyvitamin D [25(OH)D] levels and nonalcoholic fatty liver disease (NAFLD) independent of visceral obesity in Koreans and to examine whether the associations differ according to the presence of diabetes or insulin resistance.A total of 1081 adults were enrolled from a population-based cohort in Ansan city. Serum 25(OH)D concentrations were measured in all subjects. Insulin resistance was measured by homeostasis model assessment of insulin resistance (HOMA-IR). Using computed tomography, NAFLD was diagnosed if the liver attenuation index (LAI, the difference between the mean hepatic and splenic attenuation) was
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