SDBS-AEO Mixture for Triton X-100 Replacement: Surface Activity and Application in Biosensors

Autor: Zhenzhen Li, Lei Wang, Mengjie Tang, Yulong Sun, Li Zhang, Zhongxiu Chen
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Biosensors, Vol 14, Iss 10, p 505 (2024)
Druh dokumentu: article
ISSN: 2079-6374
DOI: 10.3390/bios14100505
Popis: Triton X-100 (TX-100) is a commonly used surfactant in the manufacture of biosensors. The factors limiting the use of TX-100 in biosensors are environmental concerns. In this study, the binary system of sodium dodecyl benzene sulfonate (SDBS) and fatty alcohol-polyoxyethlene ether (AEO) was investigated from the physicochemical principle of surfactant interaction and its application in biosensors. The results demonstrated that a mixture of SDBS and AEO at an appropriate molar ratio had a comparable activity to TX-100 in terms of surface activity, micelle formation, dynamic adsorption, foaming, emulsifying, and cell permeability. Theory and experimentation support the idea that SDBS-AEO might take the place of TX-100 in the manufacturing of biosensors. This study contributes to the development of alternatives to TX-100 and provides a new perspective for an in-depth study of the interaction mechanism of additives in biosensor design.
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