COVID19 infection and vascular rearrangement/ controlled angiogenesis – A new supportive therapeutic approach in patients with pre-existing ischemic and high-shear vascular conditions

Autor: Debatosh Datta, Gautam Kumar Saha, Nirmal Kumar Ganguly
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Apollo Medicine, Vol 17, Iss 5, Pp 50-54 (2020)
Druh dokumentu: article
ISSN: 0976-0016
2213-3682
DOI: 10.4103/am.am_93_20
Popis: This is an indicative mini-review on possible new therapeutics for COVID-19 with preexisting ischemic morbidities. The review highlights a new supportive therapeutic approach where lysine-induced controlled vascular organization (angiogenesis) has been demonstrated in reversal of cerebrovascular ischemic stroke which appears to be one of the few final fatal clinical outcomes of current COVID-19 infections. Further, a parallel supportive time-bound induction of fresh exchange beds, by way of rapid collateral formation, is proposed in all comorbid ischemic patients with the low-molecular-weight angiogen(s), with an objective of mitigation of tissue/organ ischemia.
Databáze: Directory of Open Access Journals