POSSIBILITIES OF OVARIAL SUPPRESSION IN HORMONE-DEPENDENT MAMMARY GLAND CANCER
Autor: | I. A. KOROLEVA, M. V. KOPP |
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Jazyk: | ruština |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Медицинский совет, Vol 0, Iss 6, Pp 152-155 (2017) |
Druh dokumentu: | article |
ISSN: | 2079-701X 2658-5790 |
DOI: | 10.21518/2079-701X-2017-6-152-155 |
Popis: | Ovarian suppression (OS) is an effective therapy in hormone-sensitive breast cancer. Oophorectomy and ovarian irradiation have historically been used to achieve the goal of ovarian ablation. Luteinizing hormone releasing hormone (LHRH) analogues have largely supplanted surgical and radiation-based approaches because of less side effects and a lower likelihood of permanent amenorrhea, with the potential for restoration of fertility. LHRH analogues goserelin, buserelin, leuprorelin are equally effective. Buserelin is economically attractive. |
Databáze: | Directory of Open Access Journals |
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