POSSIBILITIES OF OVARIAL SUPPRESSION IN HORMONE-DEPENDENT MAMMARY GLAND CANCER

Autor: I. A. KOROLEVA, M. V. KOPP
Jazyk: ruština
Rok vydání: 2017
Předmět:
Zdroj: Медицинский совет, Vol 0, Iss 6, Pp 152-155 (2017)
Druh dokumentu: article
ISSN: 2079-701X
2658-5790
DOI: 10.21518/2079-701X-2017-6-152-155
Popis: Ovarian suppression (OS) is an effective therapy in hormone-sensitive breast cancer. Oophorectomy and ovarian irradiation have historically been used to achieve the goal of ovarian ablation. Luteinizing hormone releasing hormone (LHRH) analogues have largely supplanted surgical and radiation-based approaches because of less side effects and a lower likelihood of permanent amenorrhea, with the potential for restoration of fertility. LHRH analogues goserelin, buserelin, leuprorelin are equally effective. Buserelin is economically attractive.
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