| Autor: |
Mayumi Shoji, Naoya Teramoto, Takahiro Ishikawa, Aiko Hayashi, Ai Matsumoto, Hidetoshi Ochiai, Ayano Yamaguchi, Yukari Maeda, Atsushi Takasaki, Chihiro Hiraga, Shintaro Ide, Kana Ide, Masashi Yamamoto, Yoshiro Maezawa, Ayako Shigeta, Seiichiro Sakao, Takuji Suzuki, Misuzu Yahaba, Toshihumi Taniguchi, Hidetoshi Igari, Koutaro Yokote, Masaya Koshizaka |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Endocrine and Metabolic Science, Vol 16, Iss , Pp 100196- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2666-3961 |
| DOI: |
10.1016/j.endmts.2024.100196 |
| Popis: |
Introduction: To elucidate factors associated with severe disease in patients with coronavirus disease 2019 (COVID-19) pneumonia complicated with diabetes mellitus. Methods: Among patients with COVID-19 pneumonia hospitalized from January to September 2021, 100 patients with diabetes were included in the study. Patients in the intensive care unit admission or in-hospital death category were defined as the severe group (26 patients), and the other patients as the moderate group (74 patients). Comparisons were made between the two groups. Medical histories were extracted from the medical records, and statistical analysis was performed. Results: Patients were 62.1 ± 13.0 years of age, 70 % male, 48 % aged 65 years and more, and HbA1c was 7.72 ± 1.51 %. The severe group had significantly higher blood glucose level, CRP, WBC, and LDH on admission. Serum albumin level was significantly lower in the severe group and was significantly negatively correlated with number of days on oxygen administration (r = 0.447) and maximal oxygen concentration (r = 0.561). Multiple logistic regression analysis with severity of illness as the objective variable showed that high CRP and low albumin levels on admission, and older age were independently associated. Conclusions: Low albumin levels on admission may be an indicator of severe disease in patients with diabetes. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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