Folliculotropic mycosis fungoides of the face successfully treated combining CO2 laser and conventional photodynamic therapy (c-PDT)

Autor: Biagio Scotti, Bianca Maria Piraccini, Alessandro Pileri
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Photodiagnosis and Photodynamic Therapy, Vol 50, Iss , Pp 104377- (2024)
Druh dokumentu: article
ISSN: 1572-1000
DOI: 10.1016/j.pdpdt.2024.104377
Popis: A 57-year-old male with a three-year history of folliculotropic mycosis fungoides (FMF), previously treated systemically, received CO2 laser-assisted photodynamic therapy (PDT) following the recurrence of FMF on the face. The procedure involved a CO2 laser (SmartXide DOT Deka) and the photosensitizing agent methyl aminolevulinate (MAL) (METVIX 160 mg/g Cream, Galderma Medical), in conjunction with a red light-emitting diode lamp (Aktilite CL128, Galderma, wavelength 630 nm). The primary endpoint was the clinical remission of the lesions; the secondary one the evaluation of treatment tolerance, measured using the 11-point (0–10) Numeric Rating Scale (NRS) for burning/pain, heat, and swelling. After a single treatment session and four weeks of follow-up, the patient's facial lesions achieved complete clinical remission.
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