Autor: |
Luciamare Perinetti Alves Martins, PhD, Roberto Esteves Pires Castanho, PhD, Adriano Barbosa Nogueira, Otavio Turolo da Silva, Alex Silva de Gusmão |
Jazyk: |
angličtina |
Rok vydání: |
2011 |
Předmět: |
|
Zdroj: |
Brazilian Journal of Infectious Diseases, Vol 15, Iss 2, Pp 116-118 (2011) |
Druh dokumentu: |
article |
ISSN: |
1413-8670 |
DOI: |
10.1016/S1413-8670(11)70155-6 |
Popis: |
Objective: To verify the incidence of T. cruzi transmission through breastfeeding during acute experimental Chagas’ disease. Methods: Fifteen female Swiss mice were mated and, after pregnancy confirmation, placed in individual cages. A few hours after birth, the females were inoculated with 0.1 mL of blood containing approximately 3 × 105 trypomastigote forms of Y strain of T. cruzi and continued breastfeeding for 25 days. Results: In 142 offspring examined no infection through breastfeeding was observed. Conclusions: The low number of trypomastigote forms ingested by the newborn mice combined with biological and biochemical characteristics of blood trypomastigotes may explain the lack of transmission in this experiment. Keywords: Trypanosoma cruzi, foods for pregnant and breastfeeding mothers, Chagas disease |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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