Synthesis and Characterization of Novel Unsymmetrical and Symmetrical 3-Halo- or 3-Methoxy-substituted 2-Dibenzoylamino-1,4-naphthoquinone Derivatives

Autor: Alan J. Anderson, Oladapo Bakare, Ray J. Butcher, Seshat Mack, Claudia Mouamba, Malik Lewis, Emmanuel Akinboye, Nailah Brandy, Yakini Brandy
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Molecules, Vol 18, Iss 2, Pp 1973-1984 (2013)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules18021973
Popis: Symmetrical and unsymmetrical 3-halo- or 3-methoxy- substituted 2-dibenzoylamino- 1,4-naphthoquinone analogs were synthesized with an average yield of 45% via sodium hydride promoted bis-acylation of 2-amino-3-chloro-1,4-naphthoquinone, 2-amino-3-bromo-1,4-naphthoquinone and 2-amino-3-methoxy-1,4-naphthoquinone.
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