Structural and functional brain damage in women with multiple sclerosis: A mini-review of neuroimaging sex-based studies

Autor: Antonia Ceccarelli
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in Neurology, Vol 13 (2022)
Druh dokumentu: article
ISSN: 1664-2295
DOI: 10.3389/fneur.2022.1057446
Popis: Neuroimaging literature in healthy humans has shown that there are sex-related differences in healthy brain's anatomical structure, associated function and susceptibility to neurological diseases. This mini-review summarizes findings derived from the current neuroimaging studies focused on sex-related brain structural and functional damage in women with multiple sclerosis (MS). MS is a chronic, multifactorial, immune-mediated disorder of the central nervous system that affects mostly women. Even if recent neuroimaging studies have shed light on distinctive features of sex-related MS differences in brain structural and functional damage, more research is needed to better elucidate sex-related MS pathological changes and susceptibility and to implement sex-tailored treatment strategies in MS.
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