| Autor: |
Kadidia Tounkara, Olivier Kwiatek, Mamadou Niang, Cheik Abou Kounta Sidibe, Amadou Sery, Martin Dakouo, Habib Salami, Modou Moustapha Lo, Aminata Ba, Mariame Diop, Ahmed Bezeid El Mamy, Ahmed Salem El Arbi, Yahya Barry, Ekaterina Isselmou, Habiboullah Habiboullah, Abdellahi Salem Lella, Baba Doumbia, Mohamed Baba Gueya, Joseph Savadogo, Lassina Ouattara, Germaine Minougou, Geneviève Libeau, Arnaud Bataille |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Frontiers in Veterinary Science, Vol 6 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2297-1769 |
| DOI: |
10.3389/fvets.2019.00275 |
| Popis: |
Peste des Petits Ruminants (PPR) is a viral disease affecting predominantly small ruminants. Due to its transboundary nature, regional coordination of control strategies will be key to the success of the on-going PPR eradication campaign. Here, we aimed at exploring the extent of transboundary movement of PPR in West Africa using phylogenetic analyses based on partial viral gene sequences. We collected samples and obtained partial nucleoprotein gene sequence from PPR-infected small ruminants across countries within West Africa. This new sequence data was combined with publically available data from the region to perform phylogenetic analyses. A total of fifty-five sequences were obtained in a region still poorly sampled. Phylogenetic analyses showed that the majority of virus sequences obtained in this study were placed within genetic clusters regrouping samples from multiple West African countries. Some of these clusters contained samples from countries sharing borders. In other cases, clusters grouped samples from very distant countries. Our results suggest extensive and recurrent transboundary movements of PPR within West Africa, supporting the need for a regional coordinated strategy for PPR surveillance and control in the region. Simple phylogenetic analyses based on readily available data can provide information on PPR transboundary dynamics and, therefore, could contribute to improve control strategies. On-going and future projects dedicated to PPR should include extensive genetic characterization and phylogenetic analyses of circulating viral strains in their effort to support the campaign for global eradication of the disease. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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