Intensive blood pressure control on arterial stiffness among older patients with hypertension
| Autor: | Shuyuan Zhang, Yixuan Zhong, Shouling Wu, Hailei Wu, Jun Cai, Weili Zhang, On behalf of the STEP Study Group, Jing Ni, Xuehong Zhang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Chinese Medical Journal, Vol 137, Iss 9, Pp 1078-1087 (2024) |
| Druh dokumentu: | article |
| ISSN: | 0366-6999 2542-5641 00000000 |
| DOI: | 10.1097/CM9.0000000000002868 |
| Popis: | Abstract. Background:. Arterial stiffening increases with age and blood pressure and is associated with cardiovascular disease (CVD), but the relationship between blood pressure lowering and arterial stiffening is still uncertain, especially in older people. This study aimed to evaluate the effect of intensive blood pressure treatment on the progression of arterial stiffness and risk of CVD in older patients with hypertension. Methods:. The Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients (STEP) trial was a multicenter, randomized, controlled trial performed at 42 clinical centers throughout China, and 8511 patients aged 60–80 years with essential hypertension were enrolled and randomly assigned to systolic blood pressure (SBP) target of 110 mmHg to |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|