Detection of dengue virus serotype 3 in Cajamarca, Peru: Molecular diagnosis and clinical characteristics
| Autor: | Miguel Angel Aguilar-Luis, Hugo Carrillo-Ng, Sungmin Kym, Wilmer Silva-Caso, Eduardo Verne, Luis J del Valle, Jorge Bazán-Mayra, Victor Zavaleta-Gavidia, Daniel Cornejo-Pacherres, Yordi Tarazona-Castro, Ronald Aquino-Ortega, Angela Cornejo-Tapia, Juana del Valle-Mendoza |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Asian Pacific Journal of Tropical Medicine, Vol 14, Iss 10, Pp 456-462 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2352-4146 1995-7645 |
| DOI: | 10.4103/1995-7645.326257 |
| Popis: | Objective: To describe and molecularly characterize an outbreak of dengue virus (DENV) infection in Cajamarca, an Andean region in Peru. Methods: A total of 359 serum samples from patients with acute febrile illness were assessed for the presence of DENV via RT-PCR, ELISA NS1, IgM and IgG in Cajamarca, Peru from January 2017 to June 2017. The evaluation of the different diagnostic tests and their applicability was performed. Results: Dengue virus was detected in 24.7% of samples by RT-PCR. Meanwhile, serological analysis detected 30.3% positive cases via ELISA NS1 antigen, 16.7% via ELISA IgG and 9.7% via ELISA IgM. Most of the cases corresponded to DENV-3 (77.5%). The use of RT-PCR performed better in primary infections (P |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|