Persistent IgG anticardiolipin autoantibodies are associated with post-COVID syndrome

Autor: Daniel Bertin, Elsa Kaphan, Samuel Weber, Benjamin Babacci, Robin Arcani, Benoit Faucher, Amélie Ménard, Alexandre Brodovitch, Jean Louis Mege, Nathalie Bardin
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 113, Iss , Pp 23-25 (2021)
Druh dokumentu: article
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2021.09.079
Popis: Persistence of various symptoms in patients who have recovered from coronavirus disease 2019 (COVID-19) was recently defined as ‘long COVID’ or ‘post-COVID syndrome’ (PCS). This article reports a case of a 58-year-old woman who, although recovering from COVID-19, had novel and persistent symptoms including neurological complications that could not be explained by any cause other than PCS. In addition to a low inflammatory response, persistence of immunoglobulin G anticardiolipin autoantibody positivity and eosinopenia were found 1 year after acute COVID-19 infection, both of which have been defined previously as independent factors associated with the severity of COVID-19. The pathophysiological mechanism of PCS is unknown, but the possibility of persistence of the virus, especially in the nervous system, could be suggested with a post-infectious inflammatory or autoimmune reaction.
Databáze: Directory of Open Access Journals