Electro-oculography in bilateral optic neuropathy

Autor: Padmini Dahanayake, Tharaka L. Dassanayake, Manoji Pathirage, Saman Senanayake, Mike Sedgwick, Vajira Weerasinghe
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Research Notes, Vol 13, Iss 1, Pp 1-6 (2020)
Druh dokumentu: article
ISSN: 1756-0500
DOI: 10.1186/s13104-020-05131-0
Popis: Abstract Objective Effect of bilateral, optic neuropathy on the function of retinal pigment epithelium has not been investigated extensively to date. This study aimed to determine the effect of bilateral, optic neuropathy on light peak:dark trough ratio, light peak and dark trough values of electro-oculography. Thirty-seven patients with a clinical diagnosis of bilateral optic neuropathy and 40 control subjects were recruited in this observational, cross-sectional study, carried out at the Neurophysiology unit, Teaching Hospital, Peradeniya, Sri Lanka. Pattern reversal visual evoked potentials, pattern electroretinography and electro-oculography were recorded in all of them. Results Twenty-four patients (64.9%) had reduced light peak:dark trough ratio values. The median light peak:dark trough ratio ± inter quartile range of the patient group (1.50 ± 0.4) was significantly lower than that of the controls (1.80 ± 0.2), (p
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