| Autor: |
Hong Bae Kim, Ku Youn Baik, Moon Ho Kang, Jong Hoon Chung |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Applied Sciences, Vol 14, Iss 2, p 724 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2076-3417 |
| DOI: |
10.3390/app14020724 |
| Popis: |
In this study, we investigated the effect of photobiomodulation (PBM) using near-infrared light on the dentin and periodontal ligament in a beagle model. We utilized a specific PBM device to irradiate NIR light with a wavelength of 810 nm and an energy density of 80.22 mJ/cm2. The device’s settings were optimized for a frequency of 300 Hz and a 30% duty cycle, allowing precise and controlled light exposure. Through a comprehensive analysis involving micro-computed tomography, scanning electron microscopy, and hematoxylin and eosin staining, we demonstrated increased odontoblast activity at the pulp–dentin interface in PBM-treated samples. This increased activity may be postulated to potentially contribute to alleviating dental hypersensitivity through the differentiation of dental pulp stem cells and the promotion of vascular development within the odontoblast layer. Moreover, our observations also indicated an improvement in the strength and integrity of fibrous connective tissue within the periodontal ligament. These findings highlight the potential of PBM with specific parameters applied using NIR as a valuable treatment method for tooth tissue regeneration. It shows particular promise in the treatment of dental diseases associated with dentin and periodontal ligament damage and offers a new perspective in the management of tooth hypersensitivity and other related dental diseases. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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