MRI analysis and clinical significance of lower extremity muscle cross-sectional area after spinal cord injury

Autor: Robert M Lester, Kori Johnson, Refka E Khalil, Rehan Khan, Ashraf S Gorgey
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Neural Regeneration Research, Vol 12, Iss 5, Pp 714-722 (2017)
Druh dokumentu: article
ISSN: 1673-5374
DOI: 10.4103/1673-5374.206634
Popis: Shortly after spinal cord injury (SCI), the musculoskeletal system undergoes detrimental changes in size and composition, predominantly below the level of injury. The loss of muscle size and strength, along with increased immobility, predisposes persons with SCI to rapid and severe loss in bone mineral density and other health related consequences. Previous studies have highlighted the significance of measuring thigh muscle cross-sectional area, however, measuring the size and composition of muscles of the lower leg may provide insights on how to decrease the risk of various comorbidities. The purpose of the current review was to summarize the methodological approach to manually trace and measure the muscles of the lower leg in individuals with SCI, using magnetic resonance imaging. We also intend to highlight the significance of analyzing lower leg muscle cross-sectional area and its relationship to musculoskeletal and vascular systems in persons with SCI.
Databáze: Directory of Open Access Journals