Study of Chromosomal Abnormalities in Couples with Recurrent Spontaneous Abortions (RSA) in Ardabil Province
| Autor: | Ziba Jahani, Seyyed saeid Hosseini Asl, Homa Akhavan |
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| Jazyk: | perština |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Journal of Ardabil University of Medical Sciences, Vol 18, Iss 1, Pp 91-107 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2228-7280 2228-7299 |
| Popis: | Background & objectives: The spontaneous abortion, loss of the fetus until the twentieth week of pregnancy, is one of the most common medical problems in reproductive age. Approximately 15 to 20 percent of all clinically recognized pregnancies lead to abortion. Failure in pregnancy involves economic costs, physical and mental problems for the family and the society. Recurrent spontaneous abortion is a multifactorial phenomenon and this study analyzed chromosomal abnormalities and the prevalence of consanguineous marriages in parents with recurrent spontaneous abortions in Ardabil province. Methods: A total of 350 patients with at least two spontaneous abortions were analyzed using GTG-banding cytogenetic technique. Results: Parental chromosomal abnormalities were found in 18 cases (10.28% of couples). Most of abnormalities were structural (72.2%). chromosomal aberrations were found in 10 (55.6%) females and 8 (44.4%) males. Translocations were the most common chromosomal abnormalities (55.6 %) diagnosed in this study. Also, there was a significant correlation between recurrent spontaneous abortion due to consanguineous marriage and chromosomal abnormalities (p |
| Databáze: | Directory of Open Access Journals |
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