| Autor: |
K. Slack, R. Billing, S. Matthews, H. N. Allbutt, R. Einstein, J. M. Henderson |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Parkinson's Disease, Vol 2010 (2010) |
| Druh dokumentu: |
article |
| ISSN: |
2042-0080 |
| DOI: |
10.4061/2010/427810 |
| Popis: |
The present study evaluated whether the unilateral 6-hydroxydopamine (6-OHDA) model of Parkinson's disease produces autonomic deficits. Autonomic parameters were assessed by implanting a small radiofrequency telemetry device which measured heart rate variability (HRV), diurnal rhythms of heart rate (HR), core body temperature (cBT) and locomotor activity (LA). Rats then received 6-OHDA lesion or sham surgery. 6-OHDA lesioned rats exhibited head and body axis biases, defective sensorimotor function (“disengage” test), and prominent apomorphine rotation (all P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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