Detection of a 640-bp deletion in the Aggregatibacter actinomycetemcomitans leukotoxin promoter region in isolates from an adolescent of Ethiopian origin

Autor: Rolf Claesson, Jan Gudmundson, Carola Höglund Åberg, Dorte Haubek, Anders Johansson
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Oral Microbiology, Vol 7, Iss 0, Pp 1-4 (2015)
Druh dokumentu: article
ISSN: 2000-2297
DOI: 10.3402/jom.v7.26974
Popis: The expression of the leukotoxin of Aggregatibacter actinomycetemcomitans is regulated by the leukotoxin promoter. A 530-bp deletion or an 886-bp insertion sequence (IS) element in this region has earlier been described in highly leukotoxic isolates. Here, we report on highly leukotoxic isolate with a 640-bp deletion, which was detected in an adolescent of Ethiopian origin.
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