| Autor: |
Neha Patel, Florian Stengel, Ruedi Aebersold, Matthew G. Gold |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-017-01715-w |
| Popis: |
The A-kinase anchoring protein AKAP79 is regulated by calmodulin (CaM). Here, the authors use crosslinking coupled to mass spectrometry to identify the CaM-binding site in AKAP79 and present the structure of CaM bound to an AKAP79 peptide. The structure shows that CaM adopts a highly compact conformation to interact with a mixed α/310 helix in AKAP79. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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