The characteristic of a splanchnic blood-groove at patients with the compensated and decompensated course of cirrhosis

Autor: A. S. Tugushev, N. V. Tumanska, S. M. Gulevsky, D. I. Mikhantyev, V. V. Neshta
Jazyk: English<br />Russian<br />Ukrainian
Rok vydání: 2015
Předmět:
Zdroj: Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Iss 3, Pp 71-75 (2015)
Druh dokumentu: article
ISSN: 2409-2932
2306-8094
DOI: 10.14739/2409-2932.2015.3.52681
Popis: Syndrome of portal hypertension in liver cirrhosis is determined pathogenetically by the disparity of reduced hepatic portal perfusion to the increase of flowing blood volume. The role of visceral blood flow, which determines the amount of portal blood, is not valued enough. Aim. The results of survey of 190 patients with liver cirrhosis have been studied in order to assess visceral blood flow. Methods and results. We have analyzed the clinical condition of patients, the ultrasound scan and Doppler ultrasound results, which characterize the blood flow in the portal, splenic and superior mesenteric vein, hepatic, splenic and superior mesenteric arteries. It was found that the splanchnic blood flow in liver cirrhosis is characterized by an increase in volume portal blood. The natural history of cirrhosis of the liver is accompanied by a decrease in portal blood flow relative to splenic and superior mesenteric flow in the transition from compensated to decompensated state. Conclusions. This indicates the decrease in hepatic portal perfusion relative to increase in visceral blood volume, an increase of portal pressure portacaval gradient, being one of the causes of hemodynamic complications.
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