Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety

Autor: Li-Jing Min, Yan-Xia Shi, Hong-Ke Wu, Zhao-Hui Sun, Xing-Hai Liu, Bao-Ju Li, Yong-Gang Zhang
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Applied Sciences, Vol 5, Iss 4, Pp 1211-1220 (2015)
Druh dokumentu: article
ISSN: 2076-3417
DOI: 10.3390/app5041211
Popis: A series of novel thioether derivatives containing 1,2,4-triazole moiety were designed and synthesized from 4-chlorophenol and ethyl 2-chloroacetate as starting materials by multi-step reactions under microwave irradiation, and their structures were characterized by 1H-NMR, MS and elemental analysis. The antifungal activity of title compounds was determined. The results indicated that some of title compounds exhibited moderate antifungal activity.
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