Association of polymorphisms of HLA-DRB1 and TNF-308 G/A with radiographic joint damage in patients with early rheumatoid arthritis with high inflammatory activity, treated according to the principle of 'Treat to target' (REMARKA study)

Autor: I A Guseva, A V Smirnov, N V Demidova, M Yu Krylov, A S Avdeeva, E Yu Samarkina, E L Luchikhina, D E Karateev, D D Abramov, E L Nasonov
Jazyk: ruština
Rok vydání: 2018
Předmět:
Zdroj: Терапевтический архив, Vol 90, Iss 5, Pp 38-43 (2018)
Druh dokumentu: article
ISSN: 0040-3660
2309-5342
48593826
DOI: 10.26442/terarkh201890538-43
Popis: Objective. To clarify the association between HLA-DRB1 and TNFα (-308G>A) genes polymorphism and joint destruction/further progression during 12 months of the follow-up period (FUP) in patients with early (
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