Is soft drink consumption associated with gestational hypertension? Results from the BRISA cohort

Autor: J.M.A. Barbosa, A.A.M. da Silva, G. Kac, V.M.F. Simões, H. Bettiol, R.C. Cavalli, M.A. Barbieri, C.C.C. Ribeiro
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Brazilian Journal of Medical and Biological Research, Vol 54, Iss 1 (2021)
Druh dokumentu: article
ISSN: 1414-431X
1414-431x
DOI: 10.1590/1414-431x202010162
Popis: It is still unknown whether excessive consumption of sugar-sweetened beverages may be linked to gestational hypertensive disorders, other than preeclampsia. This study investigated the association between soft drink consumption and hypertension during pregnancy, analyzing the relationship from the perspective of counterfactual causal theory. Data from pregnant women of the BRISA cohort were analyzed (1,380 in São Luis and 1,370 in Ribeirão Preto, Brazil). The explanatory variable was the frequency of soft drink consumption during pregnancy obtained in a prenatal interview. The outcome was gestational hypertension based on medical diagnosis, at the time of delivery. A theoretical model of the association between soft drink consumption and gestational hypertension was constructed using a directed acyclic graph. Marginal structural models (MSM) weighted by the inverse of the probability of soft drink consumption were also employed. Using Poisson regression analysis, high soft drink consumption (≥7 times/week) was associated with gestational hypertension in São Luís (RR=1.48; 95%CI: 1.03-2.10), in Ribeirão Preto (RR=1.51; 95%CI: 1.13-2.01), and in the two cohorts combined (RR=1.45; 95%CI: 1.16-1.82) compared to lower exposure (
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