Bioprospecting of Sechium spp. varieties for the selection of characters with pharmacological activity

Autor: María Isabel Iñiguez-Luna, Jorge Cadena-Iñiguez, Ramón Marcos Soto-Hernández, Francisco Javier Morales-Flores, Moisés Cortes-Cruz, Kazuo N. Watanabe, Ryoko Machida-Hirano, Jorge David Cadena-Zamudio
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-021-85676-7
Popis: Abstract Bioprospecting identifies new sources of compounds with actual or potential economic value that come from biodiversity. An analysis was performed regarding bioprospecting purposes in ten genotypes of Sechium spp., through a meta-analysis of 20 information sources considering different variables: five morphological, 19 biochemical, anti-proliferative activity of extracts on five malignant cell lines, and 188 polymorphic bands of amplified fragment length polymorphisms, were used in order to identify the most relevant variables for the design of genetic interbreeding. Significant relationships between morphological and biochemical characters and anti-proliferative activity in cell lines were obtained, with five principal components for principal component analysis (SAS/ETS); variables were identified with a statistical significance ( 0.5) and nine variables (
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