Use of the Guardian Connect glycemic monitoring system in patients after total duodenopancreatectomy in the early postoperative period on intravenous insulin therapy

Autor: A. G. Farmanov, E. V. Bublik, O. I. Vinogradskaya, O. V. Udovichenko, A. V. Zilov, S. M. Deunezheva, E. G. Ryzhkova, V. I. Egorov, V. V. Fadeev, A. V. Zhivov, I. E. Tobianskaya
Jazyk: English<br />Russian
Rok vydání: 2024
Předmět:
Zdroj: Сахарный диабет, Vol 27, Iss 1, Pp 59-68 (2024)
Druh dokumentu: article
ISSN: 2072-0351
2072-0378
DOI: 10.14341/DM13055
Popis: BACKGROUND: Among different subtypes of pancreatogenic diabetes mellitus the biggest difficulties of glycemic control arise in patients after total duodenopancreatectomy (TDPE), first of all due to the presence of absolute insulin insufficiency.AIM: Estimating safety and cost-effectiveness Guardian Connect CGM system in early postoperative period in hospitalized patients after TDPE on continuous intravenous insulin therapy (CIVIT).MATERIALS AND METHODS: Glucose measurement results of 26 patients in early postoperative period after TDPE were analyzed. In 12 of them, we used Guardian Connect CGM system. In this group 43 cycles (1 cycle — 6 days, 258 days total) of CGM and 971 glucometer measurements used for CGM calibration were analyzed; in other 14 patients in whom only glucometer was used we analyzed 2496 glycemic values.Cost-effectiveness was calculated over 6 days for CGM and only glucometer use (including cost of CGM, glucometers, disposable materials, clinic wage-costs to medical staff for time required for glucose control).RESULTS: Glucose levels of group #1 were in the target range 5.6 to 10.0 mmol/L (66.7 vs 61.2%, p=0.003) and the range 4.3–11.6 mmol/L (85.2% vs 82.2%, p=0.038) more than in comparison with group #2.The frequency of hypoglycemic episodes (
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