Correlation study of serum vitamin D, total IgE and eosinophils in children with atopic dermatitis

Autor: Jinling FU, Qilin LI, Chun PANG
Jazyk: čínština
Rok vydání: 2021
Předmět:
Zdroj: Pifu-xingbing zhenliaoxue zazhi, Vol 28, Iss 5, Pp 357-360 (2021)
Druh dokumentu: article
ISSN: 1674-8468
DOI: 10.3969/j.issn.1674-8468.2021.05.005
Popis: Objective Serum levels of vitamin D (VitD), total immunoglobulin E (tIgE) and eosinophil ratio (EOS%) in children with atopic dermatitis (AD) were measured in order to determine the relationship between VitD and AD, and its immunoregulatory role in AD. Methods Serum samples were collected from 120 patients with AD and 60 healthy controls. Enzyme-linked immunosorbent assay (ELISA) was performed to detect the serum levels of 25(OH)D in the AD and controls, and the total serum IgE levels in the AD group. Blood cell analyzer was used to determine the proportion of blood eosinophils in the AD group. Results The serum level of 25(OH)D was significantly lower in the AD group (62.99±17.38) nmol/L than that in the healthy controls (72.44±18.07) nmol/L(t=2.92, P
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