Design of Deterministic Model of Signal Transduction between Neuronal Cells

Autor:	Maryna A. Hliatsevich, Pavel M. Bulai, Taras N. Pitlik, Andrey A. Denisov, Sergey N. Cherenkevich
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	deterministic model synaptic transmission simulation Mathematics QA1-939
Zdroj:	Mathematical Modelling and Analysis, Vol 20, Iss 1 (2015)
Druh dokumentu:	article
ISSN:	13926292 1392-6292 1648-3510
DOI:	10.3846/13926292.2015.1002823
Popis:	Mathematical model describing signal transduction between neurons has been presented using the system of nonlinear ordinary differential equations. The Cauchy problem for the given system has been solved numerically and system parameters were adjusted to match the results of experimental measurements of extracellular postsynaptic potentials in rat hippocampus slices. While fitting model to the experimental data some values of synaptic parameters have been determined.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/45d270d3dd404a2cad540ffdab4412a9 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF