| Autor: |
L. L. Shostakovych-Koretskaya, M. A. Nikolaychuk, I. V. Budayeva, O. P. Shevchenko-Makarenko, K. Yu. Lytviy, S. V. Biletska |
| Jazyk: |
English<br />Ukrainian |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Medičnì Perspektivi, Vol 24, Iss 4, Pp 94-101 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2307-0404 |
| DOI: |
10.26641/2307-0404.2019.4.189360 |
| Popis: |
From scientific literature it is known that vitamin D helps maintain the most important functions of the immune system, there is evidence of its role in inflammatory and metabolic diseases of the liver, including infection with hepatitis C. Aim – to study vitamin D status in patients with chronic viral hepatitis C compared to the healthy ones. We examined 100 patients with chronic viral hepatitis C (main group) and 30 patients without hepatitis C virus (control group). Level of 25 (OH) D in serum was studied by immunochemical method with electrochemiluminescent detection. To verify the diagnosis of vitamin D deficiency and insufficiency, a classification (M.F. Holick, 2011), adopted by the International Institute of Medicine and the Committee of Endocrinologists for clinical practice guidelines, was used. Vitamin D deficiency was found in 44% of people with chronic viral hepatitis C in the main group (mean hydroxycalciferol – 14.36±4.12 ng/ml. Vitamin D deficiency was found in 6,6% in the control group (mean 17,5±8,52 ng/ml). The average vitamin D deficiency in the main group was slightly lower than that in the control group. Factors that affect the metabolism of vitamin D in patients with chronic viral hepatitis C include a lack of vitamin D in blood serum. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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