The Therapeutic Potential of Anthocyanins: Current Approaches Based on Their Molecular Mechanism of Action

Autor: Bahare Salehi, Javad Sharifi-Rad, Francesca Cappellini, Željko Reiner, Debora Zorzan, Muhammad Imran, Bilge Sener, Mehtap Kilic, Mohamed El-Shazly, Nouran M. Fahmy, Eman Al-Sayed, Miquel Martorell, Chiara Tonelli, Katia Petroni, Anca Oana Docea, Daniela Calina, Alfred Maroyi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Frontiers in Pharmacology, Vol 11 (2020)
Druh dokumentu: article
ISSN: 1663-9812
DOI: 10.3389/fphar.2020.01300
Popis: Anthocyanins are natural phenolic pigments with biological activity. They are well-known to have potent antioxidant and antiinflammatory activity, which explains the various biological effects reported for these substances suggesting their antidiabetic and anticancer activities, and their role in cardiovascular and neuroprotective prevention. This review aims to comprehensively analyze different studies performed on this class of compounds, their bioavailability and their therapeutic potential. An in-depth look in preclinical, in vitro and in vivo, and clinical studies indicates the preventive effects of anthocyanins on cardioprotection, neuroprotection, antiobesity as well as their antidiabetes and anticancer effects.
Databáze: Directory of Open Access Journals