Adverse effects of antiretroviral therapy in pregnant women infected with HIV in Brazil from 2000 to 2015: a cohort study

Autor:	Adriane M. Delicio, Giuliane J. Lajos, Eliana Amaral, Fabia Lopes, Fernanda Cavichiolli, Isabeli Myioshi, Helaine Milanez
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	HIV Toxicity Adverse effects Antiretroviral therapy Pregnancy Infectious and parasitic diseases RC109-216
Zdroj:	BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-14 (2018)
Druh dokumentu:	article
ISSN:	1471-2334
DOI:	10.1186/s12879-018-3397-x
Popis:	Abstract Background Antiretroviral therapy (ART) use in pregnancy presents unquestionable benefits in preventing mother-to-child transmission (MTCT) of HIV although it is associated with maternal adverse effects. The aim of this study was to evaluate the adverse effects of antiretroviral therapy in pregnant women infected with HIV. Methods Cohort study of pregnant women infected with HIV followed at the CAISM/UNICAMP Obstetric Clinic from 2000 to 2015. The following maternal adverse effects were observed: anemia, thrombocytopenia, allergy, liver function test abnormalities, dyslipidemia and diabetes. Data collected from patients’ files was added to a specific database. Descriptive analysis was shown in terms of absolute (n) and relative (%) frequencies and mean, median and standard deviation calculations. Chi-square or Fisher exact test (n
Databáze:	Directory of Open Access Journals
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