| Autor: |
So Shimamura, Honami Morikawa, Ken Shinohara, Hiroki Ohkoshi, Chisa Omori, Yuuki Hoshino, Yoshinori Uchida, Saiki Masafumi, Shinnosuke Ikemura, Naoki Ohishi, Tetsuo Kondo, Kenzo Soejima |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Respiratory Medicine Case Reports, Vol 50, Iss , Pp 102042- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2213-0071 |
| DOI: |
10.1016/j.rmcr.2024.102042 |
| Popis: |
There is no approved drug treatment for autoimmune pulmonary alveolar proteinosis (APAP), although traditionally requires complex treatments such as whole lung lavage (WLL). We herein report on a 67-year-old man diagnosed with APAP. Treatment with atorvastatin (5 mg daily) resulted in significant improvement in symptoms, lung function, and computed tomography findings, with enhanced oxygenation, although serum anti-GM-CSF antibody levels remained elevated. This case suggests that the remission observed in this case could potentially be attributed to a direct effect of atorvastatin within the pulmonary alveoli. Statins may be considered as one of the treatment options for APAP. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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