Silica-zinc chloride (SiO2-ZnCl2) catalyzed Michael addition reaction of active methylene compounds to β-nitrostyrenes: Synthesis of functionalized pyrazole derivatives
| Autor: | V. B. R. K. Krishnan, Santha Kumari Merugu, V. Siva Rama Krishna Reddy, Hari Babu Bollikolla |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Current Chemistry Letters, Vol 12, Iss 1, Pp 17-26 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1927-7296 1927-730X |
| DOI: | 10.5267/j.ccl.2022.10.001 |
| Popis: | Under solvent-free conditions, a simple and efficient procedure has been developed for the Michael addition reaction of active methylene compounds to β-nitrostyrenes. The resulting Michael adducts are efficiently converted into functionalized pyrazole derivatives with hydrazine hydrate in excellent yields. All the compounds were well characterized by spectroscopic techniques. |
| Databáze: | Directory of Open Access Journals |
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