mSphere of Influence: Combining Host and Pathogen Genetics To Disrupt Chronic Infections

Autor: Andrew J. Olive
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: mSphere, Vol 5, Iss 1 (2020)
Druh dokumentu: article
ISSN: 2379-5042
DOI: 10.1128/mSphere.00106-20
Popis: ABSTRACT Andrew J. Olive works in the field of host responses to chronic infections. In this mSphere of Influence article, he reflects on how “Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing” (Y. J. Zhang, M. C. Reddy, T. R. Ioerger, A. C. Rothchild, et al., Cell 155:1296–1308, 2013, https://doi.org/10.1016/j.cell.2013.10.045) impacted his own work using genetic approaches to dissect the interface between host and pathogen.
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