| Autor: |
Md. Harun Al Rashid, Sayani Majumder, Vivekananda Mandal, Subhash C. Mandal, Rajarajan Amirthalingam Thandavarayan |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Journal of Traditional and Complementary Medicine, Vol 9, Iss 2, Pp 106-118 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2225-4110 |
| DOI: |
10.1016/j.jtcme.2017.11.003 |
| Popis: |
Diospyros melanoxylon Roxb. (D. melanoxylon) belongs to the family Ebenaceae and its leaves are very well known for making beedi throughout the World. The current study estimated the comparative extraction technique and its in-vitro antidiabetic prospective of the leaves of D. melanoxylon. Qualitative phytochemicals analysis of the samples from D. melanoxylon was carried out for the detection of secondary metabolites. Total phenolics, flavonoids, triterpenoids and tannins content of D. melanoxylon were estimated using colorimetric assay. Microwave-assisted extraction (MAE) technique with a low carbon output was observed for the speedy extraction of bioactive compounds obtained from Diospyros melanoxylon leaf extract. MAE produced a maximum yield of bioactive compounds which was found to be more efficient than ultrasound, soxhlet and maceration extraction. Qualitative HPLC analysis was performed for bioactive compounds. The in-vitro antidiabetic assay was performed using α-amylase and α-glucosidase inhibitory activity. In conclusion, the fractions exhibited the concentration-dependent inhibitory effect with significant (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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