Serial changes of coronary flow reserve over one year after transcatheter aortic valve implantation in patients with severe aortic stenosis

Autor: Teruaki Wada, Yasutsugu Shiono, Kentaro Honda, Daisuke Higashioka, Akira Taruya, Masahiro Takahata, Suwako Fujita, Shingo Ota, Keisuke Satogami, Yuichi Ozaki, Manabu Kashiwagi, Akio Kuroi, Takashi Yamano, Kazushi Takemoto, Takashi Tanimoto, Hironori Kitabata, Yoshiharu Nishimura, Atsushi Tanaka
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Cardiology: Heart & Vasculature, Vol 42, Iss , Pp 101090- (2022)
Druh dokumentu: article
ISSN: 2352-9067
DOI: 10.1016/j.ijcha.2022.101090
Popis: Background: Impaired coronary flow reserve (CFR) portends a poor prognosis in patients with aortic stenosis. The present study aims to investigate how CFR changes over one year after transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis, and to explore factors related to the changes. Methods: Consecutive patients undergoing TAVI were registered. CFR in the left anterior descending artery was measured by transthoracic echocardiography on three occasions pre-TAVI, one-day post-TAVI, and one-year post-TAVI. Results: A total of 59 patients were enrolled, 46 of whom completed one-year follow-up. CFR was impaired in 35 (59.3%) patients pre-TAVI, but the impairment was only seen in 2 patients (4%) one-year post-TAVI. CFR value improved from 1.75 (1.50–2.10) cm/s pre-TAVI, to 2.00 (1.70–2.30) one-day post-TAVI, and further to 2.60 (2.30–3.10) one-year post-TAVI (P
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