| Autor: |
Wouter A. J. Vints, Evrim Gökçe, Julija Šeikinaitė, Simona Kušleikienė, Vida J. Česnaitienė, Jeanine Verbunt, Oron Levin, Nerijus Masiulis |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
European Review of Aging and Physical Activity, Vol 21, Iss 1, Pp 1-15 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1861-6909 |
| DOI: |
10.1186/s11556-024-00344-9 |
| Popis: |
Abstract Background The aging brain exhibits a neuroinflammatory state, driven partly by peripheral pro-inflammatory stimuli, that accelerates cognitive deterioration. A growing body of evidence clearly indicates that physical exercise partly alleviates neuroinflammation and positively affects the aging process and cognition. In this randomized controlled trial, we aimed to observe the effect of 12 weeks of resistance training (RT) on peripheral biomarker levels, cognitive function changes and their interrelationship, and explore differences in those exercise-induced changes in older adults with high risk of mild cognitive impairment (MCI) compared to older adults with low risk of MCI. Methods Fifty-two participants (aged 60–85 years old, 28 female) were randomly allocated to a 12 week lower limb RT program consisting of two training sessions per week or waiting list control group. The Montreal Cognitive Assessment (MoCA) was used to stratify participants screened as high ( |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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