Two-Stage Optimization Methods to Solve the DNA-Sample Allocation Problem

Autor:	Diego Noceda-Davila, Silvia Lorenzo-Freire, Luisa Carpente
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	scheduling linear programming Metaheuristics PCR technique DNA sequencing Mathematics QA1-939
Zdroj:	Mathematics, Vol 10, Iss 22, p 4359 (2022)
Druh dokumentu:	article
ISSN:	2227-7390
DOI:	10.3390/math10224359
Popis:	This paper deals with new methods capable of solving the optimization problem concerning the allocation of DNA samples in plates in order to carry out the DNA sequencing with the Sanger technique. These methods make it possible to work with independent subproblems of lower complexity, obtaining solutions of good quality while maintaining a competitive time cost. They are compared with the ones introduced in the literature, obtaining interesting results. All the comparisons among the methods in the literature and the laboratory results have been made with real data.
Databáze:	Directory of Open Access Journals
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