Mechanical function of the right ventricle in infants with tetralogy of Fallot
| Autor: | С. Г. Суханов, Е. Н. Орехова, Ю. С. Синельников, М. С. Суханов |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Патология кровообращения и кардиохирургия, Vol 19, Iss 3, Pp 19-25 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1681-3472 2500-3119 |
| DOI: | 10.21688/1681-3472-2015-3-19-25 |
| Popis: | Objective. The function of the right ventricle (RV) in patients with tetralogy of Fallot (ToF) largely determines the immediate and long-term results of surgical correction of the defect. The aim of this study was to evaluate the mechanical function of RV by analyzing the endocardium movement velocity in infants with ToF. Methods. The study involved 25 ToF patients 3.9±3 months old and 20 healthy children as the comparison group. The vector analysis used allowed for evaluating longitudinal strain (S) and strain rate (SR) of the right ventricle. Results. RV S was lower in ToF patients as compared to healthy ones (-11.7±4.1 against -32.1±3.9%, р It was found out that the pulmonic valve gradients correlate with RV S (Rs = 0.89 and 0.8), while inverse correlation was observed between systolic SR and the pulmonary artery trunk and branches. Mechanical remodeling of RV in patients with ToF manifests itself by a decrease in global and regional systolic and diastolic strain. Systolic Conclusion. Systolic mechanical remodeling of RV in ToF patients makes itself evident by a considerable decrease in the velocity of RV global longitudinal systolic deformation in proportion to the degree of obstruction of the outflow tract of the right ventricle. Diastolic mechanical remodeling manifests itself by pronounced impaired relaxation in the form of RV monophasic filling in the early and late diastoles. |
| Databáze: | Directory of Open Access Journals |
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