Estimate of toxically influence of silicon carbide nanoparticles according histopatologycal changes
| Autor: | Grozdanov Anita, Mladenovska Kristina, Ristoski Trpe, Vasilevska Violeta |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Macedonian Veterinary Review, Vol 36, Iss 1, Pp 25-31 (2013) |
| Druh dokumentu: | article |
| ISSN: | 1409-7621 1857-7415 |
| Popis: | Taking in consideration a very wide application of nanoparticules in different industrial sectors due to their remarkable properties for implementation in different products, very important part for future development of nanotechology is following a histopatologycal changes provoke of this material.Silicon carbide (SiC) as ceramic material with high thermal conductivity, high stability, good wear resistance and small thermal expansion coefficient is very applied in ceramic’s industry, power electronics, biomaterials, pharmaceutics etc. Histopathological changes of SiC particles were investigate on 4 weeks old female Wistar rats divided into four groups (two control and two experimental groups), sacrificed 2, 7 and 14 days after treatment. Histopathological diagnosis was performed on heart, liver, spleen, kidneys, lung, brain, gastrointestinal tract, using standard Hematoxilin-eosin staining methods. The main toxicological influences of SiC were observed on liver, lungs and gastrointestinal tract. |
| Databáze: | Directory of Open Access Journals |
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