Fever of unknown origin (FUO) in children: a single-centre experience from Beijing, China

Autor: Gang Liu, Bing Hu, Tian-Ming Chen, Shu-Ping Liu, Hui-Li Hu, Ling-Yun Guo, He-Ying Chen, Shao-Ying Li
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMJ Open, Vol 12, Iss 3 (2022)
Druh dokumentu: article
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2021-049840
Popis: Objective To date, there is no standard diagnostic practice to identify the underlying disease-causing mechanism for paediatric patients suffering from chronic fever without any specific diagnosis, which is one of the leading causes of death in paediatric patients. Therefore, we aimed this retrospective study to analyse medical records of paediatric patients with fever of unknown origin (FUO) to provide a preliminary basis for improving the diagnostic categories and facilitate the treatment outcomes.Design A retrospective study.Setting Beijing Children’s Hospital.Participants Clinical data were collected from 1288 children between 1 month and 18 years of age diagnosed with FUO at Beijing Children’s Hospital between January 2010 and December 2017.Interventions According to the aetiological composition, age, duration of fever and laboratory examination results, the diagnostic strategies were analysed and formulated.Primary and secondary outcome measures The statistical analyses were carried out using SPSS V.24.0 platform along with the χ2 test and analysis of variance (p
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