The temporal dynamics of Plasmodium species infection after artemisinin-based combination therapy (ACT) among asymptomatic children in the Hohoe municipality, Ghana

Autor:	Felix Ansah, Kwamina Nyame, Rukaya Laryea, Richard Owusu, Denick Amon, Mark-Jefferson Buer Boyetey, Dzidzor Ayeke, Nasibatu Razak, Victor E. Kornu, Sarah Ashitei, Caleb Owusu-Appiah, Jersley D. Chirawurah, James Abugri, Yaw Aniweh, Nicholas Opoku, Colin J. Sutherland, Fred N. Binka, Margaret Kweku, Gordon A. Awandare, Bismarck Dinko
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Asymptomatic malaria Plasmodium species Prevalence rate Artemisinin-based combination therapy (ACT) Parasite clearance Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216
Zdroj:	Malaria Journal, Vol 22, Iss 1, Pp 1-12 (2023)
Druh dokumentu:	article
ISSN:	1475-2875
DOI:	10.1186/s12936-023-04712-1
Popis:	Abstract Background The routine surveillance of asymptomatic malaria using nucleic acid-based amplification tests is essential in obtaining reliable data that would inform malaria policy formulation and the implementation of appropriate control measures. Methods In this study, the prevalence rate and the dynamics of Plasmodium species among asymptomatic children (n = 1697) under 5 years from 30 communities within the Hohoe municipality in Ghana were determined. Results and discussion The observed prevalence of Plasmodium parasite infection by polymerase chain reaction (PCR) was 33.6% (571/1697), which was significantly higher compared to that obtained by microscopy [26.6% (451/1697)] (P
Databáze:	Directory of Open Access Journals
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