| Autor: |
Mingcan Yu, Abdul Malik Tyagi, Jau-Yi Li, Jonathan Adams, Timothy L. Denning, M. Neale Weitzmann, Rheinallt M. Jones, Roberto Pacifici |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-019-14148-4 |
| Popis: |
T cells are involved in the bone loss induced by parathyroid hormone (PTH), but their origin is unknown. Here, the authors show that the intestinal microbiota is required for PTH to induce bone loss and describes mechanisms for microbiota-mediated gut–bone crosstalk in mouse models of hyperparathyroidism. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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