Case Report: Safety and Efficacy of Tocilizumab in a Patient with Rheumatoid Arthritis and Chronic Hepatitis C
| Autor: | Filippo Iebba, Fiorella Di Sora, Agapito Tarasi, Wilma Leti, Tatiana Montella, Francesco Montella |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Case Reports in Medicine, Vol 2012 (2012) |
| Druh dokumentu: | article |
| ISSN: | 1687-9627 1687-9635 |
| DOI: | 10.1155/2012/212381 |
| Popis: | Tocilizumab is a monoclonal humanized anti-IL-6-receptor antibody used for the treatment of rheumatoid arthritis. The safety of tocilizumab in HCV patients is an open question. We report on safety and efficacy of tocilizumab in a 71-year-old female with rheumatoid arthritis and chronic hepatitis C. Monotherapy with tocilizumab (8 mg/kg every 4 weeks, i.v.) was prescribed after the discontinuation, determined by clinical inefficacy, of anti-TNF-alfa agents (adalimumab and, subsequently, etanercept). We have registered an optimal and rapid clinical response to tocilizumab with early remission (SDAI |
| Databáze: | Directory of Open Access Journals |
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