Advancements in Radiomics for Immunotherapy of Non-small Cell Lung Cancer

Autor: Yue HOU, Tianming ZHANG, Hong WANG
Jazyk: čínština
Rok vydání: 2024
Předmět:
Zdroj: Chinese Journal of Lung Cancer, Vol 27, Iss 8, Pp 637-644 (2024)
Druh dokumentu: article
ISSN: 1009-3419
1999-6187
DOI: 10.3779/j.issn.1009-3419.2024.102.29
Popis: Lung cancer is the main cause of cancer-related deaths, with non-small cell lung cancer (NSCLC) being the predominant subtype. At present, immunotherapy represented by immune checkpoint inhibitors (ICIs) of programmed cell death receptor 1 or its ligand has been widely used in the clinical diagnosis and treatment of patients with NSCLC. However, only a few patients can benefit from it, and reliable predictive markers for immunotherapy are lacking. Radiomics is a tool that uses computer software and algorithms to extract a large amount of quantitative information from biomedical images. A large number of studies have confirmed that the radiomic model that predicts the immune efficacy of NSCLC can be used as a new type of immune efficacy predictive marker, which is expected to guide the individualized diagnosis and treatment decisions for patients with lung cancer and has a bright application prospect. This article reviews the research progress of radiomics in predicting the immune therapy response of NSCLC, identifying pseudo-progression and hyperprogression, ICIs-related pneumonia, cachexia risk, and combining with other genomics.
Databáze: Directory of Open Access Journals