Healthcare institutions’ recommendation regarding the use of FFP-2 masks and SARS-CoV-2 seropositivity among healthcare workers: a multicenter longitudinal cohort study

Autor: Katarzyna Szajek, Felix Fleisch, Sandra Hutter, Martin Risch, Theresa Bechmann, Valerie A. Luyckx, Sabine Güsewell, Cédric Hirzel, Alexia Cusini, AMICO Study Group
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Antimicrobial Resistance and Infection Control, Vol 11, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2047-2994
DOI: 10.1186/s13756-021-01047-x
Popis: Abstract Background Health care workers (HCW) are heavily exposed to SARS-CoV-2 from the beginning of the pandemic. We aimed to analyze risk factors for SARS-CoV-2 seroconversion among HCW with a special emphasis on the respective healthcare institutions’ recommendation regarding the use of FFP-2 masks. Methods We recruited HCW from 13 health care institutions (HCI) with different mask policies (type IIR surgical face masks vs. FFP-2 masks) in Southeastern Switzerland (canton of Grisons). Sera of participants were analyzed for the presence of SARS-CoV-2 antibodies 6 months apart, after the first and during the second pandemic wave using an electro-chemiluminescence immunoassay (ECLIA, Roche Diagnostics). We captured risk factors for SARS-CoV-2 infection by using an online questionnaire at both time points. The effects of individual COVID-19 exposure, regional incidence and FFP-2 mask policy on the probability of seroconversion were evaluated with univariable and multivariable logistic regression. Results SARS-CoV-2 antibodies were detected in 99 of 2794 (3.5%) HCW at baseline and in 376 of 2315 (16.2%) participants 6 months later. In multivariable analyses the strongest association for seroconversion was exposure to a household member with known COVID-19 (aOR: 19.82, 95% CI 8.11–48.43, p
Databáze: Directory of Open Access Journals
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