Plasmodium vivax resistance to chloroquine (R2) and mefloquine (R3) in Brazilian Amazon region Resistência do Plasmodium vivax pela cloroquina (R2) e mefloquina (R3) na amazônia Brasileira

Autor:	Maria das Graças C. Alecrim, Wilson Alecrim, Vanize Macêdo
Jazyk:	angličtina
Rok vydání:	1999
Předmět:	Plasmodium vivax Resistência a drogas Resistência à cloroquina Resistência à mefloquina Drug resistance Chloroquine resistance Mefloquine resistance Arctic medicine. Tropical medicine RC955-962
Zdroj:	Revista da Sociedade Brasileira de Medicina Tropical, Vol 32, Iss 1, Pp 67-68 (1999)
Druh dokumentu:	article
ISSN:	0037-8682 1678-9849
DOI:	10.1590/S0037-86821999000100013
Popis:	We report for the first time a patient with malaria due to Plasmodium vivax who showed R2 resistance to chloroquine and R3 resistance to mefloquine in the Brazilian Amazon region based on WHO clinical criteria for diagnosis of malaria resistance. Failure was observed with unsupervised oral chloroquine, chloroquine under rigorous supervision and mefloquine in the same scheme. Finally, the patient was cured with oral artesunate.Estamos relatando pela primeira vez um paciente com malária por Plasmodium vivax que mostrou resistência R2 à cloroquina e resistência R3 à mefloquina na Amazônia brasileira, de acordo com os critérios clínicos da OMS para resistência da malária. A falha foi observada com cloroquina oral, não supervisionada, cloroquina oral administrada sob rigorosa supervisão e com mefloquina no mesmo esquema. A paciente curou com o artesunato oral.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/3e0d6d10774b49b0935947ed258fa9ff Zobrazit plný text záznamu View record in DOAJ