Evaluating the prognostic value of systemic immune‐inflammatory index in patients with acute decompensated heart failure

Autor: Jiajun Qiu, Xin Huang, Maobin Kuang, Chao Wang, Changhui Yu, Shiming He, Guobo Xie, Zhiyong Wu, Guotai Sheng, Yang Zou
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: ESC Heart Failure, Vol 11, Iss 5, Pp 3133-3145 (2024)
Druh dokumentu: article
ISSN: 2055-5822
DOI: 10.1002/ehf2.14904
Popis: Abstract Aims The value of the systemic immune‐inflammatory index (SII) in assessing adverse outcomes in various cardiovascular diseases has been extensively discussed. This study aims to evaluate the predictive value and risk stratification ability of SII for 30 day mortality in patients with acute decompensated heart failure (ADHF). Methods This analysis included 1452 patients hospitalized for ADHF, all the participants being part of the China Jiangxi‐acute decompensated heart failure1 project. The risk stratification capability of the SII in patients with ADHF, as well as its correlation with the 30 day mortality risk among ADHF patients, was evaluated utilizing Kaplan–Meier survival analysis and multivariable Cox regression models. A restricted cubic spline was employed to model the dose–response relationship between the two, and the receiver operating characteristic curve was utilized to assess the predictive ability of SII for 30 day mortality. Results The Kaplan–Meier analysis revealed that the risk of mortality in the high SII group (SII ≥ 980 × 109/L) was significantly greater than that in the low SII group (SII
Databáze: Directory of Open Access Journals