Lack of direct association between oral mucosal lesions and SARS-CoV- 2 in a cohort of patients hospitalised with COVID-19
| Autor: | Gabriela Schwab, Michelle Palmieri, Rodrigo M. Zerbinati, Dmitry J. S. Sarmento, Thais Reis, Karem L. Ortega, Italo T. Kano, Rafael A. V. Caixeta, Bengt Hasséus, Dipak Sapkota, Roger Junges, Simone Giannecchini, André L. F. Costa, Sumatra M. C. P. Jales, José A. L. Lindoso, Camila Barros Gallo, Paulo H. Braz-Silva |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Oral Microbiology, Vol 14, Iss 1 (2022) |
| Druh dokumentu: | article |
| ISSN: | 20002297 2000-2297 |
| DOI: | 10.1080/20002297.2022.2047491 |
| Popis: | Background COVID-19 is a disease affecting various human organs and systems, in which the virus seeks to interact with angiotensin-converting enzyme 2 receptors. These receptors are present in the oral cavity, but the direct relationship between such an interaction and possible oral manifestations of COVID-19 is still unclear.Aim The present study evaluated oral manifestations in a cohort of COVID-19 patients during the period of hospitalisation.Methods In total, 154 patients presenting moderate-to-severe forms of COVID-19 had their oral mucosa examined twice a week until the final outcome, either discharge or death. The oral alterations observed in the patients were grouped into Group 1 (pre-existing conditions and opportunistic oral lesions) and Group 2 (oral mucosal changes related to hospitalization).Results Oral lesions found in the patients of Group 1 are not suggestive of SARS-CoV-2 infection as they are mainly caused by opportunistic infections. On the other hand, oral alterations found in the patients of Group 2 were statistically (P |
| Databáze: | Directory of Open Access Journals |
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